Issue 6 Articles

RECENT ARTICLES

  • May 22, 2019
    The technique and instrument of microsurgery has significantly improved in recent years. Free flap transfers become the popular methods of reconstruction for the head and neck surgery after extirpation of cancer. Immediate reconstruction with two- teams approaches after tumor abla- tion becomes routine procedure and has allowed the successful rates more than 95% in most of centers...
  • May 22, 2019
    Acute promyelocytic leukemia(APL),a specific characteristic of t(15;17) chromosomal translocation,molecular gene analyses are conclusive in vivo evidence that oncogenic pml/RARa fusion plays a crucial role in APL leukemogenesis [1-3]. Since the introduction of initial 13-cis retinoic acid(13-cis RA)[4],and currently all-trans RA(ATRA) [5] and tamibarotene [6],RA plus chemotherapy or RA plus As2O3 regimen is currently the standard of care [7]...
  • May 02, 2019
    Nivolumab, a fully human IgG4 monoclonal antibody inhibitor of Programmed Death-1 (PD-1) was suggested to provide potential survival benefit in patients with advanced, chemotherapy-refractory Esophago Gastric Junction (EGJ) adenocarcinoma. An acidic tumor microenvironment is reported to be associated with suppression of cancer immunity and it is reported that the alkalization effect of bicarbonate enhanced the effect of anti-PD-1 therapy in mouse models of melanoma...
  • March 11, 2019
    According to the classic prognostic criteria based on the "TNM" staging system, it has been ac-cepted that small tumors (T1) without lymph node involvement (N0) are always "good news", and this is based on the benefits of mammographic screening. However, advances in molecular biology and genetics, with the emergence of gene expression plat-forms, have come to question it...
  • February 25, 2019
    Neulasta Onpro kit eliminates need for additional clinic visit after chemotherapy. Given the racially diverse population in our institution, we investigated acceptance of Onpro kit among patients on chemotherapy.Single-institution, retrospective review conducted in patients with GI tumors who received Onpro kit within 1 hour of completion of systemic chemotherapy from Jan 2014 through Jan 2018...