Oncology Solutions: Empowering Cancer Diagnosis and Treatment
Gentaur Clinics of Oncology specializes in comprehensive cancer diagnostics and innovative treatment solutions. As a global biotechnology supplier, Gentaur provides state-of-the-art oncology tools and reagents that support early detection, personalized therapy, and advanced cancer research. Our product line includes genetic testing kits, tumor biomarker panels, cell culture reagents, and immunotherapy solutions designed to meet the needs of hospitals, research labs, and cancer treatment centers.
Cancer is a genetic disease that arises from alterations in DNA, disrupting normal cell growth and division. At Gentaur, we support clinicians and scientists in understanding these complex mutations and developing targeted strategies to combat all types of cancer from solid tumors to hematological malignancies. With fast delivery across Europe and expert customer support, Gentaur is your trusted partner in the fight against cancer.
Cavernous Sinus Metastasis of Leiomyosarcoma with Orbital Extension along the Third Nerve, Mimicking Cavernous Sinus Meningioma
Leiomyosarcoma (LMS) metastasis in the central nervous system is extremely rare. Metastatic LMSs have been described in the orbit, meninges, and skull base, however there are no reports of LMS metastasis into the cavernous sinuswith primary origin from lower extremity and long silent disease period of 7 years..
Incorporate Experiences as a Medical Oncologist to Enlighten Severe Loss of a Loved One: An Optimistic Perspective
You are working as a medical oncologist, being familiar to guide patients with incurable cancer. Often, your patients are severely ill. Although a large majority of these patients will eventually be cured, there are also patients entering either a short or long-term disease trajectory in which they are aware of the incurable nature of their disease as well as its prospect of (slow) deterioration.
Sustained Response to Temozolomide Rechallenge after Hematological Toxicity in MGMT Methylated Glioblastoma
Background: Glioblastoma Multiforme (GBM) is known to have a rapidly progressive and fatal clinical course. Methylation of the methylguanine DNA methyltransferase promoter (MGMT) has been associated with a more indolent clinical course and better response to the alkylating agent temozolomide. The standard of care treatment includes radiotherapy with concurrent temozolomide (75mg/m2) followed by adjuvant temozolomide for 6 months (150 mg/m2 at month one, followed by 200mg/m2 given for the remaining 5 months).
Inelastic Mean Free Path and Stopping Power of Electrons in Biomaterials
The inelastic mean free path and stopping power in organic and inorganic compounds are investigated and calculated using Drude dielectric formation. The minimum values of inverse mean free path ?-1 for organic and inorganic compounds at energy transfer ? 100 eV, while ?-1 distinguishable with previous work of Ashely (1988) and Garcia (2017)....
Explore the Frontlines of Cancer Care
Our Clinical Oncology section offers cutting-edge insights into cancer diagnosis, treatment, and research. Whether you're a healthcare professional, researcher, or patient, discover expert-driven content on the latest therapies, clinical trials, and innovations in personalized oncology. Join us in advancing cancer care and improving outcomes one breakthrough at a time.
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- Oncology is a specialized medical field dealing with the diagnosis, treatment and follow-up care of cancer patients. It is a genetic disease caused by changes to genes that control the way our cells function, especially how they grow. Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and divide to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place. When cancer develops, however, this orderly process breaks down. As cells become more and more abnormal, old or damaged cells survive when they should die, and new cells form when they are not needed. These extra cells can divide without stopping and may form growths called tumors.
Clinics of Oncology is an universal access dedicated journal which includes peer review process and focuses on origin, development, diagnosis, staging and treatment of cancer. The journal aims to drive forward the field of oncology and publishes novel, descriptive and explanatory information for mutual sharing of knowledge. This journal covers original research articles, case reports, review articles, Clinical images, manuscripts, letter to the editors, short commentaries, editorials etc..
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A Real-World Study of Safety, Immunogenicity and Efficacy of Bevacizumab in Patients with Solid
The aim of this study was to evaluate the post-marketing safety, tolerability, immunogenicity and efficacy of Bevacizumab (manufactured by Hetero Biopharma) in a broader population of patients with solid tumors.
CT Appearance of Hypervascular Pancreatic Metastases from Renal Cell Carcinoma before and after Treatment with Sunitinib in One Case
The pancreas is an unusual site for tumor metastases, accounting for only 2-5% of all cancers. The renal cell carcinoma as primitive tumour represent the most common pancreatic metastases.
Unlike other forms of non-renal malignancies affecting the pancreas secondarily, which are often associated with widespread systemic disease, renal cell carcinoma may spread to the pancreas as the only secondary site, causing an isolated involvement of the pancreas. Ppancreatic metastatic disease is often discovered during routine surveillance imaging for primary lesions or as an accidental finding on imaging performed for other reasons [1]. With advances in pancreatic surgery a resection , can now be performed safely and is associated with long-term survival in most cases [1, 2]. In fact, surgery is considered the gold standard therapy for the disease. However, the opportunity for surgical exploration is limited. Patients with multiple metastatic sites and widespread systemic disease at the time of diagnosis are not good candidates for resection. These patients usually undergo biological therapy with sunitib (tyrosine kinase inhibitors and molecular targeted therapy, which have been introduced into clinical practice for the treatment of metastatic RCC. 2 Vascular endothelial growth factor (VEGF) inhibitors and the mammalian target of rapamycin (mTOR) radically changed the outcome of patients with metastatic renal cell carcinoma, which was typically a chemoresistant disease [2]. For all these reasons, it is essential to reach an early radiological diagnosis of relapse in order to choose whether to perform a metastesectomy or continue with medical therapy
Preoperative Short-Course Chemoradiotherapy (SC CRT) with Delayed Surgery for Locally Advanced Rectal Cancer : A Single Center Experience
1. Purpose: To evaluate tolerability and efficacy of preoperative SC CRT in patients with locally advanced rectal cancer.
2. Materials and Methods: 94 patients with locally advanced rectal cancer were included in the study. The patients were treated with SC CRT: conformal radiotherapy with a total dose of 25 Gy in five fractions and chemotherapy (5-fluorouracil or capecitabine administered on the day of radiotherapy), followed at 11 weeks (average delay time) by surgery and adjuvant chemotherapy (5-fluorouracil or capecitabine). Effects of therapy were followed by 3-year disease-free survival (DFS) and overall survival (OS) rates. 
Intra-cystic (Encapsulated) Papillary Carcinoma of Breast:
A Case Report & Review of Literature1. AbstractWe are reporting a case of 62-year-old lady who presented with nipple discharge without palpable lesion and after radiographic and pathologic investigations, diagnosed as intracystic papillary carcinoma of breast. They account for less than 3% of all breast tumors and comprises a wide range of proliferative breast diseases. It is a difficult task to diagnose encapsulated papillary carcinoma. Most of the lesions present asymptomatically with or without palpable lesion or nipple discharge.
Higher Rates of Helicobacter Pylori Infection and Gastric Intestinal Metaplasia in the Asian Population in the United States
The rate of Helicobacter pylori (H. pylori) infection is higher in minority patients in the United States . Gastric intestinal metaplasia (IM) is associated with H. pylori infection and carries an increased risk for gastric cancer over time, in particular for patients from regions of high gastric cancer incidence . We aimed to compare the rates of Helicobacter pylori infection and gastric intestinal metaplasia...
IRF5 Promotes the Progression of Hepatocellular Carcinoma and is Regulated by Trim35
The IRF family of proteins involves in the tumor progression. However, but the functions of IRF5 in the tumorigenesis are largely unknown. Here, IRF5 was found to be up-regulated in hepatocellular carcinoma (HCC). Interfering with IRF5 inhibited the growth and tumorigenic ability of HCC cells. When studying the molecular mechanism, it was found that TRIM35 interacted with IRF5, promoting the ubiquitination and degradation of IRF5. In the clinical specimens of HCC, TRIM35 was negatively correlated with the expression of IRF5. These observations reveal the oncogenic function of IRF5 in the progression of HCC, suggesting that IRF5 is a promising target for the therapy of HCC.
The Role of Immunity in Chemotherapy-Resistant Patient with Pembrolizumab: A Case Report
Approaches are limited for treating advanced Non-Small-Cell Lung Cancer (NSCLC) with multidrug resistance but without ALK and EGFR mutations. Pembrolizumab (KEYTRUDA) brings on unprecedented clinical benefit in various cancer types...
The Use of the Infrared Laser Therapy of 890-910 NM for the Treatment Breast Cancer (Experimental and Clinical Study)
The experimental studies were conducted with Walker's carcinosarcoma n256, cancer of the mammary gland (RMK-1). Spontaneous –mice with mammary glands cancer (type B). The tasks were as follows: to study the effect of different doses LLLT on the growth of experimental tumors. Evaluation of the effectiveness by applying LLLT in combination with various chemotherapeutic agents (vincristin, 5-Fu, ciclophosphan). Research of LLLR effect on different types of tumors show that this treatment can be used for tumors-statistic effect and for increasing life-span in animals. Applying LLLR in combination with chemotherapeutic agents causes tumors-static action. The most effective combination was LLLT + vincristin which caused the inhibition of tumor growth in Walker's carcinosarcoma-by 92,87%, in RMK-1 - by 90,29% in comparing to controls. The combination of LLLT with HpD showed - the effect of laser therapy takes place in 30 min before the irradiation and is accompanie
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Gentaur provides a wide range of oncology-related products, including tumor biomarker kits, genetic testing tools, cell culture reagents, antibodies, and immunotherapy solutions. This one-stop-shop approach saves labs time and ensures consistency across experiments.
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With strategic warehouses across Europe and partnerships worldwide, Gentaur ensures rapid delivery of critical research tools and diagnostic kits. Researchers and clinicians get the products they need without delays, accelerating both discovery and treatment workflows.
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Gentaur offers not only products but also scientific expertise. Technical support, protocol optimization, and product recommendations help customers maximize research success and diagnostic accuracy—especially in complex areas like oncology and molecular biology.
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